Which statement about long-term corticosteroid therapy is NOT correct?

• A. Never abruptly discontinue
• B. Report any signs of infection immediately
• C. Cataracts are a side effect
• D. It is safe to take on an empty stomach

Answer: (D)

Long-term corticosteroid therapy requires careful management of GI safety, infection risk, and potential systemic effects. Do not abruptly discontinue these drugs because the adrenal glands need time to recover their own cortisol production; stopping suddenly can lead to an adrenal crisis. Because steroids suppress the immune response, signs of infection should be reported promptly so they can be evaluated and treated early. Cataracts are a known long-term side effect of extended corticosteroid use, reflecting their impact on ocular tissues. It is not safe to take a corticosteroid on an empty stomach; they can irritate the gastric lining and increase the risk of gastritis, ulcers, and GI bleeding. Taking them with meals or snacks helps protect the stomach.