Which of the following is a common gastrointestinal issue associated with cystic fibrosis?

• A. Fecal retention/impaction
• B. Nausea
• C. Diarrhea
• D. Vomiting

Answer: (D)

In cystic fibrosis, thick, sticky mucus in the gut slows intestinal movement and leads to stool buildup. The most characteristic gastrointestinal complication is distal intestinal obstruction syndrome, which presents as fecal retention or impaction. This happens because the stool becomes thick and hard to pass, causing cramps, abdominal distension, and sometimes vomiting as the obstruction develops. So, among the options, fecal retention/impaction best reflects the common CF-related GI issue. Vomiting can occur with obstruction but isn’t the typical CF GI problem; diarrhea is more related to fat malabsorption from pancreatic insufficiency, and nausea is nonspecific.