Which of the following is a proton pump inhibitor?

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Multiple Choice

Which of the following is a proton pump inhibitor?

Explanation:
Proton pump inhibitors reduce gastric acid by blocking the final step of acid production in the stomach—the hydrogen-potassium ATPase (the proton pump) on parietal cells. By shutting down this pump, they dramatically lower acid output, helping heal ulcers and alleviate GERD symptoms. Omeprazole is a proton pump inhibitor, so it fits this mechanism and is commonly used for those conditions. Other options work differently: sucralfate protects the mucosa by forming a coating, loperamide slows gut peristalsis to treat diarrhea, and ranitidine (an H2 blocker) decreases acid by blocking histamine receptors on parietal cells rather than inhibiting the proton pump.

Proton pump inhibitors reduce gastric acid by blocking the final step of acid production in the stomach—the hydrogen-potassium ATPase (the proton pump) on parietal cells. By shutting down this pump, they dramatically lower acid output, helping heal ulcers and alleviate GERD symptoms. Omeprazole is a proton pump inhibitor, so it fits this mechanism and is commonly used for those conditions.

Other options work differently: sucralfate protects the mucosa by forming a coating, loperamide slows gut peristalsis to treat diarrhea, and ranitidine (an H2 blocker) decreases acid by blocking histamine receptors on parietal cells rather than inhibiting the proton pump.

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