Losartan, Valsartan, and Candesartan are examples of which drug class?

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Multiple Choice

Losartan, Valsartan, and Candesartan are examples of which drug class?

Explanation:
These drugs block the action of angiotensin II at the AT1 receptor, which lowers blood pressure by preventing angiotensin II–mediated vasoconstriction and aldosterone release. Losartan, valsartan, and candesartan do this by binding to the AT1 receptor, so their effects come downstream of the ACE step. Because they don’t inhibit ACE, they don’t raise bradykinin levels and don’t share the cough side effect sometimes seen with ACE inhibitors. They’re also not beta blockers or calcium channel blockers, which work through different mechanisms to reduce blood pressure.

These drugs block the action of angiotensin II at the AT1 receptor, which lowers blood pressure by preventing angiotensin II–mediated vasoconstriction and aldosterone release. Losartan, valsartan, and candesartan do this by binding to the AT1 receptor, so their effects come downstream of the ACE step. Because they don’t inhibit ACE, they don’t raise bradykinin levels and don’t share the cough side effect sometimes seen with ACE inhibitors. They’re also not beta blockers or calcium channel blockers, which work through different mechanisms to reduce blood pressure.

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