IV proton pump inhibitors are given for which condition?

• A. Gastric ulcer bleeding
• B. GERD
• C. Ulcer prophylaxis
• D. None of the above

Answer: (A)

IV proton pump inhibitors are used when rapid, deep suppression of gastric acid is needed, such as in active upper GI bleeding from a gastric ulcer. The IV route ensures quick onset and reliable acid control, which helps stabilize the clot and promote healing in a patient with a gastric ulcer bleed or when someone cannot take medications by mouth. For GERD, PPIs are typically given orally for chronic reflux and esophagitis, with IV use reserved for specific in-hospital situations rather than routine treatment. Ulcer prophylaxis aims to prevent ulcers in high-risk patients and is not the scenario described by an active gastric ulcer bleed. So the best match is gastric ulcer bleeding.