Isotretinoin is what?

• A. A pain reliever
• B. A vitamin supplement
• C. A cholesterol-lowering drug
• D. Accutane (acne med)

Answer: (D)

Isotretinoin is a potent retinoid used for severe nodular acne that hasn’t responded to other treatments; its brand name Accutane is often how it’s referred to. It isn’t a pain reliever, a vitamin supplement, or a cholesterol-lowering drug. It works by shrinking the oil-producing sebaceous glands and reducing overall oil production, which helps clear acne. Because it is highly teratogenic, use requires strict pregnancy prevention and monitoring—pregnancy tests and contraception before and during treatment under programs like iPLEDGE. It can also cause liver enzyme elevations and lipid changes, plus mood-related effects, so regular lab tests and mental health monitoring are essential during therapy. Use is limited to appropriate candidates under close supervision.