Isotretinoin is primarily used to treat which condition?

• A. Severe acne
• B. Psoriasis
• C. Eczema
• D. Rosacea

Answer: (A)

Isotretinoin is a systemic retinoid used chiefly for severe, nodulocystic acne that hasn’t responded to other treatments. It works by significantly shrinking the oil-producing sebaceous glands, reducing sebum production, normalizing the way skin cells shed in hair follicles, and dampening the inflammatory processes in acne. This combination targets the central problems of severe acne and can prevent scarring, which is why it’s chosen for those cases. It isn’t a typical treatment for psoriasis, eczema, or rosacea, which involve different skin pathology and are managed with other medications. Because of its strong teratogenic risk and potential effects on liver function and lipids, it requires careful monitoring and stringent pregnancy prevention measures.