In a cystic fibrosis patient, which of the following is a priority in the initial assessment?

• A. Airway patency and SpO2 monitoring
• B. Blood glucose management
• C. Renal function assessment
• D. Liver function tests

Answer: (A)

The priority in the initial assessment of a cystic fibrosis patient is airway patency and oxygenation. CF causes thick, sticky mucus that can rapidly obstruct airways, lead to atelectasis, and cause hypoxemia. Checking airway patency focuses on whether the patient can clear secretions and maintain an open airway, while SpO2 monitoring provides real-time data on gas exchange. If oxygenation is compromised, urgent interventions (airway clearance, bronchodilators, supplemental oxygen) are needed to prevent respiratory failure.

Other systems are important for overall care, but they do not dictate immediate action during the first assessment. Blood glucose, renal function, and liver function tests reflect longer-term management and organ status rather than the urgent threat to breathing and oxygen delivery.