During IV infusion of potassium chloride, what is commonly felt at the IV site?

• A. No sensation
• B. Irritation and discomfort at the site
• C. Itching at the arm
• D. Fever

Answer: (B)

Potassium chloride given by IV is irritating to veins. The solution is concentrated and caustic to venous tissue, so as it infuses many people feel a burning or sore sensation at the IV site. This local discomfort signals vein irritation or early phlebitis, especially when the line is small, the solution is not adequately diluted, or the rate is too high. To minimize this, use a dilute solution in a suitable vein, preferably a larger peripheral vein or a central line if needed, and control the rate with an IV pump while regularly assessing the site. If pain, redness, swelling, or any signs of infiltration occur, stop the infusion and reassess the IV site to prevent tissue injury. Fever or itching would point to other issues, not the common local IV reaction from potassium chloride.